Abstract
To evaluate the influence of the pre-treatment with 2.5% nanoparticulate chitosan (2.5% NanoChi) solution on eroded dentin before the restorative dental treatment. The sample consisted of 22 patients (age between 33 and 52 years) with shallow or medium erosion lesions located in two homologous teeth. The teeth were randomly assigned according to dentin treatment: with 2.5% NanoChi and without with chitosan (control). The NanoChi were applied immediately after acid etching. The teeth were restored with Single Bond Universal (3 M) and Charisma resin (Kulzer). Analyzes were done using modified USPHS (retention, secondary caries, marginal adaptation, and sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at 7 days (baseline) and 1 year. Population demographics, Kaplan–Meier estimates and log-rank test (Mantel–Cox) were calculated for 1 year (α = 0.05). No significant difference was found in the survival rates between groups (p > 0.05) at 7 days and 1 year after treatment. After 7 days, 100% of the restorations were scored as Alpha on all criteria. After 1 year, 91% of the NanoChi restorations were scored as Alpha and 9% as Charlie for the retention, marginal adaptation, and anatomical form criteria, while 86% of the control restorations (without NanoChi) received the Alpha score and 14% received the Charlie. Secondary caries, sensitivity, color, and marginal pigmentation criteria were scored as Alpha in 100% of the restorations. The biomodification of eroded dentin with 2.5% NanoChi did not influence the survival of the restorations after 1 year. The application of 2.5% NanoChi on eroded dentin did not increase failures of resin restorations after 1 year and it can be used as a pre-treatment solution.
Highlights
Dental erosion is the irreversible and progressive loss of tooth structure caused by non-bacterial chemical processes with different etiological factors [1] that allow it to be classified as intrinsic and extrinsic
Dentin collagen degradation has generally been associated with poor clinical performance of composite resin restorations [10]
This study aimed to evaluate the influence of 2.5% w/w nanoparticulate chitosan (2.5% NanoChi) solution on eroded dentin biomodification at baseline (7 days) and final (1 year) periods before the restorative treatment, by clinical and photographic examination using modified United States Public Health Service (USPHS) criteria
Summary
Dental erosion is the irreversible and progressive loss of tooth structure caused by non-bacterial chemical processes with different etiological factors [1] that allow it to be classified as intrinsic and extrinsic. The erosion process can affect both enamel and dentin. The demineralization of the inorganic phase of the tooth exposes the prisms and reduces microhardness [7]. The dissolution of the peritubular portion and demineralization of intertubular dentin exposes the organic matrix, forming a rough and porous surface that increases the enzymatic degradation of collagen, impairing the adhesive interface in the restorative therapy [8, 9]. Dentin collagen degradation has generally been associated with poor clinical performance of composite resin restorations [10].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Materials Science: Materials in Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
