Abstract
Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medical Outcomes Study Short Form-36 (SF-36) health status questionnaire was used to measure the HRQoL and compare the mean scores of the questionnaire subscales and physical and mental component summaries (PCS and MCS) of 33 patients with MetS, 18 patients with MSDs, and 30 apparently healthy (AH) subjects. Regression analysis was used to measure the prediction power of the study group, age and gender of the participants in estimating the HRQoL. Results: Results showed that the mean scores of the physical subscales, the PCS, the mental subscales and MCS were arranged in descending order from AH subjects, patients with MetS, to patients with MSDs. The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404). The study group and age accounted for 41.8% of the variability of PCS while the study group accounted for 19.6% of the variability in the MCS. The resulted equation to estimate the PCS score was as follows: PCS = 113.18 - 12.85 (Group: 0 for AH, 1 for MetS, and 2 for MSDs) - 0.67 age. On the other hand the resulted equation to estimate the MCS score was as follows: MCS = 76.203 - 10.426 (Group: 0 for AH, 1 for MetS, and 2 for MSDs). Conclusion: Patients with MetS and patients with MSDs had lower HRQoL than AH subjects. All the physical and mental dimensions of HRQoL are negatively influenced with MetS and with MSDs with the only exception for the GMH subscale. The physical and mental burden of MSDs is more dominant. The study group and age can be used to predict the PCS while the study group can be used to predict the MCS.
Highlights
The World Health Organization has extended the definition of health beyond the absence of disease to include the state of complete physical, mental, and social well-being and the healthcare for patients with chronic disease aimed to delay death and to promote health and quality of life [1]-[3]
Patients with Metabolic Syndrome (MetS) and patients with Musculoskeletal Disorders (MSDs) from the outpatient clinics of King Khaled University Hospital, Riyadh, Saudi Arabia and age-matched apparently healthy (AH) subjects from Riyadh city community were recruited for this study
The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404)
Summary
The World Health Organization has extended the definition of health beyond the absence of disease to include the state of complete physical, mental, and social well-being and the healthcare for patients with chronic disease aimed to delay death and to promote health and quality of life [1]-[3]. During the last three decades, the HRQoL has become a significant marker of disease burden and an important outcome of healthcare for patients with chronic diseases [5] [6]. Some investigators claimed that MetS is associated with an increased risk for psychiatric comorbidity, stress, and impaired HRQoL [9]-[11]. Components of the MetS including obesity, and hypertension, have been associated with reduced HRQoL, leading some investigators to suggest that MetS itself may be associated with impaired HRQoL [18]
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