Abstract
Objective: To determine the frequency and impact of metabolic syndrome (MS) in patients with low back pain in rheumatology unit in Benin. Patients and Methods: Analytic cross-sectional study conducted between June and December 2016 in the rheumatology hospital unit of National Hospital University Hubert Koutoukou Maga of Cotonou. 82 patients with mechanical low back pain were selected. The prevalence of MS was defined using the criteria of the International Diabetes Federation 2005. The data were analyzed using epi data and SPSS17.0 software. Results: The mean age was 50.4 ± 14.9 [12 - 90] years. The sex ratio was 0.82. 29.3% patients have met diagnostic criteria for MS. The mean duration of back pain was 40 ± 17.2 [3 - 120] days. Diseases associated with low back pain were as follow: lumbar intervertebral disk degeneration (34.1%), disk herniation (13.4%), facet joint arthrosis (18.3%), degenerative spondylolisthesis (11%), degenerative lumbar spinal stenosis (6.1%) and related forms (17.1%). MS observed in 24 patients was characterized by the frequent association of abdominal obesity (24 cases), arterial hypertension (22 cases), HDL hypocholesterolemia (8 cases), hyperglycemia (12 cases) or hypertriglyceridemia (7 cases). The presence of the MS was associated with a decreased response to the medical treatment (p 0.01). Conclusion: The MS is frequent in patients with low back pain in rheumatology unit at Cotonou and influence the treatment response. The management of these patients must be integrated into a multidisciplinary approach including the rheumatologist and nutritionist.
Highlights
IntroductionObesity increases the risk of radiographic osteoarthritis
Patients and Methods: Analytic cross-sectional study conducted between June and December 2016 in the rheumatology hospital unit of National Hospital University Hubert Koutoukou Maga of Cotonou. 82 patients with mechanical low back pain were selected
metabolic syndrome (MS) observed in 24 patients was characterized by the frequent association of abdominal obesity (24 cases), arterial hypertension (22 cases), HDL hypocholesterolemia (8 cases), hyperglycemia (12 cases) or hypertriglyceridemia (7 cases)
Summary
Obesity increases the risk of radiographic osteoarthritis. The association with hip and hand osteoarthritis is weaker, but it implies that excess adipose tissue produces humoral factors, altering articular cartilage metabolism [2] [3]. It has been postulated that the leptin system could be a link between metabolic abnormalities in obesity and increased risk of osteoarthritis [2] [3] [4]. Low back pain is the first pattern in rheumatology in Benin. It predominates in the young adult, the elderly and in both sexes. The aim of this study was to determine the frequency and impact of metabolic syndrome (MS) in patients with low back pain in rheumatology Unit in Benin
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