Abstract

British Journal of Clinical PharmacologyVolume 10, Issue 5 p. 527-530 Free Access Influence of meso-caval shunt surgery on verapamil kinetics, bioavailability and response. M Eichelbaum, M EichelbaumSearch for more papers by this authorM Albrecht, M AlbrechtSearch for more papers by this authorG Kliems, G KliemsSearch for more papers by this authorK Schafer, K SchaferSearch for more papers by this authorA Somogyi, A SomogyiSearch for more papers by this author M Eichelbaum, M EichelbaumSearch for more papers by this authorM Albrecht, M AlbrechtSearch for more papers by this authorG Kliems, G KliemsSearch for more papers by this authorK Schafer, K SchaferSearch for more papers by this authorA Somogyi, A SomogyiSearch for more papers by this author First published: November 1980 https://doi.org/10.1111/j.1365-2125.1980.tb01800.xCitations: 25AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References EICHELBAUM, M. & SPANNBRUCKER, N. (1977). Rapid and sensitive method for the determination of antipyrine in biological fluids by high pressure liquid chromatography. J. Chromatogr., 140, 288– 292. GEORGE, C.F. (1979). Drug kinetics and hepatic blood flow. Clin. Pharmacokin., 4, 433– 448. GUGLER, R., LAIN, P. & AZARNOFF, D.L. (1975). Effect of portacaval shunt on the disposition of drugs with and without first-pass effect. J. Pharmac. exp. Ther., 195, 416– 423. HUET, M., Le LORIER, J., POMIER, G. & MARLEAN, D. (1979). Bioavailability of lignocaine in normal volunteers and cirrhotic patients. Clin. Pharmac. Ther., 25, 230. METZLER, C. (1969). A user's manual for Nonlin. Technical Report 7292/69/7292/005, Kalamazoo, Michigan: Up-john Company. NEAL, E.A., MEFFIN, P.J. GREGORY, P.B. & BLASCHKE, T.F. (1979). Enhanced bioavailability and decreased clearance of analgesics in patients with cirrhosis. Gastroenterology, 77, 96– 102. SCHOMERUS, M., SPIEGELHALDER, B., STIEREN, B. & EICHELBAUM, M. (1976). Physiological disposition of verapamil in man. Cardiovascular Res., 10, 605– 612. SHAND, D.G. & RANGNO, R.G. (1972). The disposition of propranolol. 1. Elimination during oral absorption in man. Pharmacology, 7, 159– 168. SPIEGELHALDER, B. & M. EICHELBAUM (1977). Determination of verapamil in human plasma by mass fragmentography using stable-labelled verapamil as internal standard. Arzneimittel-Forsch., 27, 94– 97. WAGNER, J.G. (1976). Linear pharmacokinetic equations allowing direct calculation of many needed pharmacokinetic parameters from the coefficients and exponents of polyexponential equations which have been fitted to the data. J. Pharmacokinet. Biopharmac., 4, 443– 467. Citing Literature Volume10, Issue5November 1980Pages 527-530 ReferencesRelatedInformation

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