INFLUENCE OF MEAN OFFICE BLOOD PRESSURE(BP) LEVELS ON MORTALITY IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)

Abstract

Objective: Heart failure (HF) is a major public health problem and one of the leading causes of ospitalisations and death. HFpEF is related to hypertension (HT) either in the pathogenesis and outcome, particularly in the elderly, and is becoming an increasingly worrisome health issue due to higher life expectancies in Western Countries. This study aimed to evaluate the influence of BP and its control in elderly patients with HFpEF. Design and method: Retrospective study in outpatients older than 80 years with stable HFpEF, seen in a University Hospital. Data were obtained from electronic medical records with prior authorization from the Ethics Committee. For the analysis, the first measured Office BP levels were used. Results: 106 patients were included. For Systolic BP (SBP) analysis, we use three cut-off points of SBP (measured in the office at the first visit): <░90░mmHg, between 90–139░mmHg and >░140░mm Hg. For Diastolic BP (DBP) we used two cut-off points: <░70 and >░70░mm Hg. As for the characteristics, the only differences were that those with Low SBP had significantly lowered LVEF compared to those with normal or high SBP (54% vs 59 p 0.035). As for DBP, those with low DBP had significantly lowered heart rate than those with high DBP (72░bpm vs 79░bpm, p 0.039). There were no mortality differences between those with low SBP, normal SBP and high SBP fx8, neither among patients with low DBP nor normal/high DBP. Kaplan Meier curve showed a non-significant trend to higher mortality on those with lower values of BP Conclusions: In our study, we did not observe differences in mortality between patients with low normal or high SBP, neither on those with high, normal nor low DBP. Although there may be a selection bias and this is a retrospective study, more studies are needed to assess the influence of BP control on the evolution of HFpEF in octogenarian patients with stable disease.