INFLUENCE OF MALARIAL TREATMENT ON THE SPINAL FLUID IN GENERAL PARALYSIS

Abstract

I shall report data to illustrate the influence of malaria treatment, without subsequent arsenical therapy, on the spinal fluid observations in general paralysis. These data consist of observations on: the cell count in ninety cases, quantitative determinations of the total protein in the spinal fluid in sixteen cases in which the patients were treated recently and in thirty-eight patients under observation for two years or longer subsequent to treatment, and quantitative determinations of the Wassermann reaction in the spinal fluid in forty-seven cases over a post-treatment period of from two to three and three-fourths years. The Vernes test 1 has been applied in the majority of these cases, and this will form the subject of a future communication. The results are reported without reference to the work of others; of the latter, a comprehensive bibliography will be found in the recent article of Ferraro and Fong. 2 CELL COUNT A