Abstract
IntroductionThe influence of low birth weight on development of hypertension and chronic kidney disease progression was confirmed in adolescent and adult population. There has been scarce data published on this topic in younger children and toddlers. PurposeThe aim of the study was to assess the influence of low birth weight on blood pressure and kidney volume in youngest children. Material and methodsThe study group consisted of 38 children (2–3 years), born with low birth weight. The control group consisted of 35 children, born with normal birth weight. Kidneys size and volume were assessed in ultrasonography. Serum cystatin and urine albumin concentrations were assessed. Blood pressure was taken on 4 limbs with oscillometric method. ResultsThere was tendency for the study group to have lower weight (Z-score −1.1418 vs. −0.5092, p=0.0507). They have lower height and lower head and chest circumference. They tended to have lower total kidney volume (52474mm3vs. 57451mm3, p=0.055), but that relation disappeared after adjustment to body height. There was no significant difference in blood pressure values and between GFR estimated with Filler formula (125.9 vs. 134.2, p=0.16). ConclusionsPresented study revealed no significant influence of low birth weight on kidney size and function in children in 2nd and 3rd year of life.
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