Abstract
The necessity of long-term venous access in cancer patients appears at frequent and long-term courses of cytotoxic therapy. Peripheral veins of forearms are most often used for these aims. The conditions of peripheral venous channel in 32 cancer patients, who underwent the long-term treatment with antitumor preparations were analyzed in the article on own investigatory material. The methods of dopplerography, morphological and immunohystochemical studies were used. The qualitative and quantitative dopplerographic changes in forearm veins in different terms after chemotherapy start were revealed in most patients. The conclusion was made about unsuitability of forearm peripheral veins for the long term administration of cytostatics and the necessity to create the alternative vascular access that would correspond to the criteria of safety, reliability and long-term exploitation.
Highlights
According to the data of international cancer-registers of different countries, during last 50 years the improvement of cancer patients treatment results took place that was manifested by the increase of general relapse-free survival rate at the main cancer localizations [1]
Materials and methods The work is based on the analysis of the results of examination, treatment and observation of 32 patients (18 men and 14 women) with histologically confirmed diagnosis of malignant neoplasm, who were on treatment in Vinnitsya and Zaporozhye cancer dispensaries during 2012–2015
Extravasation of cytostatics always led to the limitation of extremity functions, development of septic state, disorder of antitumor therapy protocols and worsening of patient’s life quality
Summary
According to the data of international cancer-registers of different countries, during last 50 years the improvement of cancer patients treatment results took place that was manifested by the increase of general relapse-free survival rate at the main cancer localizations [1]. It became possible due to the early diagnostics and realizations of the programs of populational screening and at the expanse of intensification of antitumor therapy methods [2]. Today the effective treatment of cancer patient can be realized in radical, palliative and symptomatic regime and include the components of accompaniment theraphy. All technologies of antitumor theraphy need creation of reliable long-term access to the patient’s vascular system. The necessity of long-term access to blood of a cancer patient appears at frequent and longterm courses of cytotoxic therapy, biotherapy, transfusion of blood and its components, hydration, supporting therapy (total parenteral nutrition, system administration of antibiotics or colony-stimulating factors), methods of efferent therapy (different methods of cytopheresis or reinfusion of marrow at its autotransplantation), pain therapy and other methods of radical, palliative and symptomatic treatment [4]
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