Abstract
Five-week-old female albino rats were given daily doses for 1 or 2 weeks of lead as acetate ranging from 2 μg to 40 mg by gastric intubation and sacrificed on the 8th or 15th day of the experiment. Calcium-45 and 85Sr were used as markers to assess the calcium and strontium transfer through the duodenal wall by the everted gut sac method of Wilson and Wiseman. Doses of lead acetate greater than 20 μg per day decreased the transfer of both calcium and strontium across the duodenal wall and these transfers decreased further with increased doses of lead, an effect which was independent of whether the rats were killed on the 8th or 15th day of the experiment. Doses of lead acetate greater than 200 μg per day, however, did not produce a further decrease in these transfers. The retention of both calcium and strontium in the intestinal wall was unaffected by the lead treatment.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
