Abstract
The ionic strength dependence of DNA mediated charge transport was studied on a DNA binding polyamide-modified electrode by the electrochemical method. The differential pulse voltammetry peak potential of (Ru(NH3)6) 3+ shifted negatively as the support electrolyte concentration increased. A linear relationship was observed between the peak potential and ionic strength in the solution at moderate salt concentrations. This could be interpreted with Debye-Huckel theory using formal potential as abridge, which linked experiments results and theoretically calculated values. At high salt concentrations, this linear relationship deviated from Debye-Huckel theory prediction because it was outside the range of validity. Without added salt in the solution, the fully charged DNA duplex will strongly attract the probe molecule (Ru(NH3)6) 3+ to the broadened p-stack of a DNA-polyamide complex, which facilitates DNA mediated charge transport.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
