Abstract
The aim: Determination of cardioprotective effect of interval normobaric hypoxia in medical rehabilitation of patients with COPD. Materials and methods: 123 patients with COPD who received basic drug therapy were examined and were divided into 2 groups. Patients of the main group (93 persons) additionally received 2 courses of 20 sessions of interval normobaric hypoxia. All patients underwent echocardiographic examination at the beginning and after 1 year of follow-up. Results: Prior to treatment, all patients had changes in the myocardium of both ventricles, due mainly to hypoxic and inflammatory effects and to a lesser extent to increased pulmonary artery pressure. Interval normobaric hypoxytherapy caused adaptive-adaptive reactions of the cardiovascular system, which manifested a positive effect on the state of both left and right ventricles: increase in stroke volume and expulsion fraction, decrease in E-DV and E-SV of the left and right ventricular E-DS, elimination of myocardium. However, the result is more effective in patients with GOLD 1 and GOLD 2 compared to GOLD 3. Conclusions: The use of interval normobaric hypoxytherapy in the rehabilitation of COPD, initiated by ischemic preconditioning, is pathogenetically justified because it triggers endogenous mechanisms of cardioprotection and metabolic adaptation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.