Abstract

Objective To compare the effects of sodium potassium magnesium calcium and Glucose Injection, 5% Glucose Injection and 9% Sodium Chloride Injection on children with blood glucose, blood lactic acid and blood gas electrolyte during operation on children. Methods patients were randomly divided into A group(sodium potassium magnesium calcium and Glucose Injection group,n=20), B group(5% sodium chloride glucose injection, n=20)and C group(9% Sodium Chloride Injection group, n=20). Blood glucose, blood lactic acid, arterial blood Gas and electrolytes were measured and compared before infusion (T0)and on postoperative time(T1). Results blood glucose in B group increased but decreased significantly in C group(P < 0.05).;Blood lactic acid in C group significantly decreased than the other two groups(P < 0.05); Mg2+ decreased in B and C groups(P < 0.05). Conclusion Sodium Potassium Magnesium Calcium and Glucose Injection has the same efficacy and safety as commonly used 5% sodium chloride glucose injection and 9% sodium chloride injection, when infused in pediatric patients during perioperative period.

Highlights

  • The focus of fluid management of children is the maintenance of environment stabilization during the perioperative period

  • This study aims to study the influence of Sodium Potassium Magnesium Calcium and Glucose Injection on changes of blood glucose, blood lactic acid and blood gas and electrolyte of children during the perioperative period so as to provide theoretical basis for its clinical application to children

  • The children were randomly divided into three groups: the group of Sodium Potassium Magnesium Calcium and Glucose Injection (Group A), the group of 5% dextrose injection (Group B) and the group of 9% parenteral solution (Group C)

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Summary

Introduction

The focus of fluid management of children is the maintenance of environment stabilization during the perioperative period. Because children have their unique characteristics in terms of the dissection and physiology compared with those of adults, there have long been controversies in terms of the selection of transfusion liquid during the perioperative period [1]. Its composition is quite similar to extracellular fluid of human body and it is widely used for adults’ water complement and the maintenance of electrolyte balance of the body in clinical practice. Few studies have focused on its effectiveness and security when it is used to children

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