Abstract
THE development of nutritional muscular dystrophy in the growing chick is known to be modified by a number of nutritional factors. Dam et al. (1952) showed that concomitant dietary deficiencies of both vitamin E and sulfur amino acids are necessary for the appearance of this disorder. In addition, inclusion of selenium in the diet has been reported to reduce although never completely prevent the incidence of muscular dystrophy (Dam and Sondergaard, 1957; Nesheim and Scott, 1958). The use of unusually high dietary levels of antioxidants other than vitamin E may also prevent the development of muscular dystrophy (Machlin and Shalkop, 1956). Recently Calvert et al. (1964) have shown that dietary linoleic acid is necessary for the appearance of muscular dystrophy, and that chicks fed linoleic acid-free diets do not show symptoms of the disease regardless of the deficiency of vitamin E and sulfur amino acids.Unpublished results from our laboratory…
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