Abstract
Summary The effects of daily injections of bovine growth hormone on growth and cerebral cortical nucleic acid metabolism were investigated in 25-day-old hypothyroid rats which had been radiothyroidectomized at 1 day of age. Growth hormone elicited an increase in body and brain weights of hypothyroid animals although the increase in weight could not be considered a result of an enhanced maturation. Nucleic acid levels and the kinetics of incorporation of labeled orotic acid into cerebral RNA in hypothyroid rats were not restored to normal by growth hormone. It was concluded that growth hormone probably does not directly contribute to brain development, at least in the absence of thyroid hormones, and that any effect may depend upon the concurrent addition of thyroid hormones.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
