Abstract

BackgroundThere are conflicting data on the influence of meal intake on the QT interval. MethodsTen healthy subjects were studied before and after a standardized breakfast and lunch with a sequence of supine resting, standing and exercise. Data collection was performed using a 12-lead Holter with semi-automated analysis. QT correction was performed using Fridericia (QTcF) correction formula and a subject-specific method based on individual QT/RR-regression (QTcI). ResultsMeal intake induced significant changes in HR (p<0.001), but not in QTcF (p=0.512) or QTcI (p=0.739). Postural analysis showed only significant differences in supine position for HR (p=0.010), not when standing or during exercise. ConclusionFood intake induced an increase in heart rate limited to supine position. Using QTcF and QTcI no QTc changes were found.

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