Influence of feeds contaminated by microscopic fungi on the physiological state of animals

Abstract

Today feeding disorders (deficiency of crude protein and limiting amino acids), the use of feed contaminated with microscopic fungi can lead to immune depression. When feeding dysfunctional feed, the live weight gain of young animals and fattening pigs is reduced by 10-90%, depending on the balance and completeness of the rations in terms of nutrients. The article assesses the degree of contamination of feed with microscopic fungi and studies the effect of eliminating the deficiency of crude protein, lysine and methionine on the health status and weight gain of laboratory rats when feeding moldy wheat grain. A balanced for essential amino acids feed allows reducing the stress of the body's defense system from the negative effects of saprophytes. An experiment was carried out on 200 (10 groups, n = 20) weaned rats of the Wistar line in order to comparatively study the consequences of feeding the diets containing wheat grain contaminated with fungi of the genera Aspergillus and Penicillium, deficient and balanced to the norms of the requirement for crude protein and two essential amino acids - lysine and methionine. The number of micromycete reaches 109 CFU (spores) in 1 gram of feed. These molds are dangerous because of the possibility of their spores entering the body of animals and germinating in the lungs, liver, kidneys, heart, intestines, reproductive organs, and muscle tissue. Once in the blood, mold spores spread throughout the body. A complete zootechnical analysis of grain was carried out in the toxicology laboratory using the methods of zootechnical and biochemical analyzes of feed, livestock products and metabolic products. The negative effect of microscopic fungi on the health indicators of white rats is less pronounced with a balanced diet for essential amino acids. A decrease in the tension of immunity, expressed in a decrease in T-cell deficiency and activation of phagocytosis, was determined. The average daily gain on the contaminated feed decreased by no more than 20%, while the gain on the contaminated diet was 50-60% lower.