Abstract

a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.

Highlights

  • Natural products have been a prolific source and an inspiration for numerous medicinal agents with widely divergent chemical structures and biological activities.[1]

  • Microbial biocontrol strategy of plant diseases has been considered as a potential tool in recent years because chemical control by the use of synthetic fungicides results in the accumulation of harmful chemical residues, which may lead to serious ecological problems.[3]

  • The antagonist agent, Aspergillus species were isolated from green residue that has decomposed for 45 days in red agricultural soil by the method of serial dilutions

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Summary

Introduction

Natural products have been a prolific source and an inspiration for numerous medicinal agents with widely divergent chemical structures and biological activities.[1] The resistance of fungi to fungicides is one of the topical issues and is increasingly of research interest.[2] Microbial biocontrol strategy of plant diseases has been considered as a potential tool in recent years because chemical control by the use of synthetic fungicides results in the accumulation of harmful chemical residues, which may lead to serious ecological problems.[3] Biocontrol is environmentally safe and in some cases is the only option available to protect plants against pathogens.[4] The biological control agents with antifungal activity include oils, phytohormones, antifungal proteins, and antifungal peptides.[5] In the biocontrol of plant diseases, the focus is usually on the augmented introduction of antagonists to control diseases.[6] Sources of biocontrol agents (BCAs) are microorganisms such as fungal and bacterial strains.[7,8,9,10] There are a variety of mechanisms of antagonistic microorganisms; nutritional and spatial competition, parasitism as well as secretion of bioactive substances, which is the most important mechanism.[11]

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