Abstract
PurposeOpen-ended and iteration-based time trade-off (TTO) tasks can both be used for valuation of health states. It has so far not been examined how the elicitation procedure affects the valuation of experience-based health states. The purpose of this study is to investigate the influence of elicitation procedure on experience-based health state values elicited by the TTO method.Methods156 Chinese adults with type 2 diabetes participated in face-to-face interviews with an open-ended or an iteration-based TTO task. The association between the type of TTO task and the valuation of health states was investigated through multiple linear regression analyses. A modified open-ended TTO task was also developed (n = 33) to test whether different phrasings of open-ended TTO tasks influence TTO values.ResultsHigher TTO values were observed in the original open-ended TTO task compared to the iteration-based task, which indicates that the elicitation procedure influences the valuation of health states. When the modified open-ended task was introduced, the difference between the two elicitation procedures was no longer statistically significant, suggesting that the phrasing and/or visual presentation of the TTO task may influence the valuation of health states.ConclusionsThe choice of elicitation procedure as well as the description of experience-based TTO tasks may influence the valuation of health states. Further research is warranted, also in other cultural contexts, to further explore these findings.
Highlights
The Quality-Adjusted Life Year (QALY) is a common outcome measure in economic evaluation of health technologies [1]
The purpose of this study is to investigate the influence of elicitation procedure on experience-based health state values elicited with the time trade-off (TTO) method
To the best of the authors’ knowledge, this is the first study to investigate the influence of elicitation procedure—openended and iteration-based—on experience-based health state values elicited with the TTO method
Summary
The Quality-Adjusted Life Year (QALY) is a common outcome measure in economic evaluation of health technologies [1]. TTO values can be elicited using an open-ended question in which the respondent is asked to directly state how many years in full health that he or she finds of equal value to the fixed number of years in the state with less than full health (open-ended TTO) Using this procedure is both time and cost saving and makes it possible to collect TTO data in large population-based surveys. The health state value is calculated by dividing the number of years in full health that makes the respondent indifferent between the two alternatives with the fixed number of years in the state with less than full health This version has been used in the development of several value sets based on valuation of hypothetical health states for EQ-5D [5,6,7,8,9, 11, 12, 20,21,22,23]
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