Abstract
Recently, all over the world, breeding work has been carried out with the active use of the methods of modern genetics. The article presents the results of a study of the relationship between the DNA markers of calpastatin (CAST) and leptin (LEP 387) with the meat productivity of Edilbaev sheep, as well as KAP 1.3 with the wool productivity of Caucasian sheep. It was revealed that these DNA markers have a sufficient level of polymorphism in the studied breeds, as well as presence of a relationship between the genotypes of the studied DNA markers with the productivity of the studied breeds.
Highlights
One of the approaches to increasing the efficiency of breeding work is use of DNA markers that allow selection of parental forms at the gene level, that is, selection by genotype directly at the DNA level [11, 12].The calpastatin gene (CAST) is one of the promising candidate genes associated with the rate of body weight gain, the quality of sheep meat and other economically useful traits, the level of manifestation of which is directly related to the economic success of sheep breeding [1, 7]
The article presents the results of a study of the relationship between the DNA markers of calpastatin (CAST) and leptin (LEP 387) with the meat productivity of Edilbaev sheep, as well as KAP 1.3 with the wool productivity of Caucasian sheep
It was revealed that these DNA markers have a sufficient level of polymorphism in the studied breeds, as well as presence of a relationship between the genotypes of the studied DNA markers with the productivity of the studied breeds
Summary
One of the approaches to increasing the efficiency of breeding work is use of DNA markers that allow selection of parental forms at the gene level, that is, selection by genotype directly at the DNA level [11, 12]. The calpastatin gene (CAST) is one of the promising candidate genes (markers) associated with the rate of body weight gain, the quality of sheep meat and other economically useful traits, the level of manifestation of which is directly related to the economic success of sheep breeding [1, 7]. A number of studies have shown the relationship of calpastatin with lethal yield, fat percentage, birth weight and average daily gain [6, 9]. One of the best studied DNA markers associated with meat production is the leptin gene (LEP 387), known as the "obesity gene". The relationship between the leptin gene and the fat tail size and the average daily weight gain in sheep has been shown [2, 5]. Identification of the polymorphism of this gene and its variability with fiber diameter will be a priority in sheep breeding in selection and breeding work [4, 8]
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