Abstract
The infectivity of six strains of T. congolense was compared in eight species of vertebrate hosts and the ability of the trypanosomes to develop in culture medium when isolated from the blood of such hosts was investigated. The six strains were infective for rats, mice, rabbits, sheep, goats and dogs, but only three were infective for guinea-pigs and two for domestic pigs. The trypano somes caused heavy infections in rats and mice, but the infections in the other species were less virulent. When the six strains were cultured from rats and rabbits five developed, only three isolated from mice and dogs grew in culture and two and one developed from sheep and goats respectively. All three strains from guinea-pigs grew, as did isolations from domestic pigs. Possible explanations for the influence of the host species on the ability of the strains to develop and grow in the culture media are discussed.
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