Abstract

The aim of the work is to assess the degree of influence of chronic intoxication with copper-zinc pyrite ore on the basis of changes in the leukocytogram and cellular composition of the rat blood. On the model of experimental intoxication of outbred white rats it was shown that a chronic excessive intake of heavy metals into the body from copper-zinc pyrite ore for 3 months leads to an increased level of cadmium, copper, iron and decreased content of zinc, cobalt in blood, lowers the level of hemoglobin, erythrocytes, leukocytes, lymphocytes, membrane resistance of blood erythrocytes, changes the leukocyte formula.

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