Abstract
The influence of changes in myocardial contractility on the height and slope of the calibrated left apex cardiogram were studied with use of a calibrated force transducer that permits recording of the left apex cardiogram in millimeters of mercury. Simultaneous registration of the calibrated left apex cardiogram and left ventricular pressure and their calibrated first derivatives was performed in 16 anesthetized dogs before and after pharmacologic interventions. Under various hemodynamic conditions, a highly significant correlation was found between the maximal value of the first derivatives of left ventricular pressure and the calibrated left apex cardiogram ( r = 0.88, P r = 0.67, P r = 0.68, P r = 0.46, P
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