Abstract
Background: Carotid intima media thickness (CIMT) is used as a surrogate measure of coronary artery disease. The aim of this research was to evaluate the effects of laparoscopic sleeve gastrectomy (LSG) and laparoscopic gastric plication (LGP), and its associated weight loss, on CIMT. Materials and Methods: This prospectively designed study enrolled 48 consecutive obese subjects who underwent either LSG or LGP between January 2013 and June 2014. Patient demographic data (age, sex, height, and weight), body–index (BMI), and metabolic parameters (lipid profile) were measured before and 3 and 6 months after surgery. The degree of liver steatosis was also determined ultrasonographically at the same time. Results: LSG was performed in 25 patients (LSG group) and LGP in 23 patients (LGP group). Both groups were similar in terms of age, sex, BMI, and CIMT preoperatively. In both groups, biochemical parameters improved significantly at 3 and 6 months after surgery. Mean CIMT decreased significantly in both groups. Conclusion: In addition to the improvement in lipid profiles of obese patients after either LGP or LSG, CIMT decreases after bariatric surgery. This decrease is proportional to the decrease in BMI and cholesterol levels. The risk of future cardiovascular events in obese subjects undergoing bariatric surgery may be decreased.
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