Abstract
Methods We enrolled 32 patients operated for severe mitral regurgitation. Half of the patients had no history of AF constituting the SR group. The remaining half had concomitant RFA for longstanding persistent AF, the RFA group. Intraoperative transesophageal echocardiography was used for tissue Doppler indices (TDI) data acquisition at the left atrial (LA) lateral wall. During post-procedural data acquisition all patients were in SR. LA biopsies were obtained during surgery and quantified for fibrosis after Mallory’s trichrome staining.
Highlights
Establishment of sinus rhythm (SR) following radiofrequency ablation (RFA) for longstanding persistent atrial fibrillation (AF) is not necessarily an equivalent to physiological atrial mechanical activity
Intraoperative transesophageal echocardiography was used for tissue Doppler indices (TDI) data acquisition at the left atrial (LA) lateral wall
Atrial mechanical contraction was noted in both groups following surgery, TDI values of late diastolic strain rate (SRI A’) and tissue velocity (TVI A’) were superior in the SR group (-1.49 ± 1.04 vs. -2.82 ± 1.97, p = 0.022; 1.22 ± 1.08 vs. 3.86 ± 2.30, p = 0.003)
Summary
We aimed to determine the influence of atrial ultrastructural remodeling on the recovery of its mechanical transport following restitution of SR
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