Abstract
BackgroundHypertension is a chronic medical condition in which blood pressure in the arteries is elevated. Given the large proportion of dental implant patients using antihypertensive medications, it is crucial to evaluate the effects of these drugs on the clinical parameters of osseointegrated implants. The aim of the present retrospective cohort study was to evaluate the influence of antihypertensive medications on clinical peri-implant tissue parameters.MethodsThirty-five patients received a total of 77 anodized dental implants. Based on the history of the use of antihypertensive medications, the patients were divided into two groups: the group taking antihypertensive medications (AH group) and the group of healthy patients (H group). Implants were followed up clinically and radiologically, with a focus on the peri-implant soft tissue parameters probing pocket depth, bleeding on probing, modified plaque index, and marginal peri-implant bone level stability.ResultsNone of the implants were lost, and no technical failures occurred. The mean follow-up duration was 7 years and 1 month. A significant difference was observed in the probing pocket depth 3.8 ± 1.3 mm in the AH group and 3.0 ± 0.7 mm in the H group. In the AH and H groups, 26.5% (9/34) and 4.7% (2/43) of the patients were diagnosed with peri-implantitis at the implant level, respectively.ConclusionsOur findings suggest some correlations between antihypertensive medication use and clinical parameters in anodized peri-implant tissue.
Highlights
Hypertension is a chronic medical condition in which blood pressure in the arteries is elevated
Description of the study patients and implants Seventy-seven implants (34 in the AH group and 43 in the H group) in 35 patients were included in this retrospective cohort study
The results of multivariate analysis in our study revealed that the antihypertensive medication affects the development of peri-implantitis
Summary
Hypertension is a chronic medical condition in which blood pressure in the arteries is elevated. Given the large proportion of dental implant patients using antihypertensive medications, it is crucial to evaluate the effects of these drugs on the clinical parameters of osseointegrated implants. The aim of the present retrospective cohort study was to evaluate the influence of antihypertensive medications on clinical peri-implant tissue parameters. Systemic diseases may impair the host’s barrier function and immune defense against periodontal pathogens, creating an opportunity for destructive periodontal disease and likely peri-implant diseases. Systemic diseases and medications may interfere with healing in peri-implant sites and increase the risk of biological complications and implant failure [7]. It could be estimated that 70 to 79% of men aged 55 years and older are classified as having hypertension
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