Abstract
The effects of different anthracyclinic antibiotics on the passive electrical properties of the membranes of normal human erythrocytes have been investigated by means of radiowave electrical conductivity measurements in the frequency range from 10 kHz to 100 MHz where interfacial polarization at the membrane surface occurs. These effects are discussed on the basis of morphological alterations induced in the cell architecture by the different drugs investigated and observed by means of freeze-fracturing and scanning electron microscopy.
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