Abstract
Aspergillus clavatus spores have been immobilized in poly(vinyl alcohol) criogel (PVAC) for ribonucleae (RNase) production. The enzyme productivity and growth of free (FC) and immobilized cells (IC) were studied in a bioreactor with agitation under different cultivation conditions. The influence of some medium compunds, aeration, and agitation speeds were investigated. Production of RNase was stimulated by the presence of reducing glucose, peptone, and soybean concentrations in the medium. From 42,000 to 45,000 U/L were produced by IC using optimized batch fermentation conditions. The RNase prouction by IC was 2.3 and 2.5 times greater than the same by FC in a bioreactor and control flasks, respectively.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
