Abstract
AimsOur aim was to evaluate, in a second data analysis of the prospective randomized controlled trial conducted by Austrian Urogynaecology Working Group, the effect of age, BMI and parity at the time of surgery on short- and long-term outcomes of women primarily treated for SUI (stress urinary incontinence) with midurethral slings.MethodsIn the original study 554 patients received randomly a retropubic (TVT) or a transobturator midurethral (TVT-O) sling procedure. 480 (87%) and 277 (50%) patients were available for a follow-up efficacy evaluation at 3 months and 5 years respectively.ResultsHigher age and BMI at surgery appear to lead to a larger probability to have a positive stress test 5 years after surgery, but not after 3 months. Older patients seem to have a worse perception of improvement 5 years after surgery as compared to younger ones, as described by the PGI-I score. Age and BMI do not affect significantly the quality of life of women surgically treated for SUI, as reflected by the results of King´s Health Questionnaire. Parity does not seem to have any effect on objective and subjective surgical outcomes.ConclusionsHigher age and BMI at surgery have a detrimental influence on the objective cure rate at 5 years after midurethral sling surgery; higher age also has a negative influence on subjective long-term outcomes. However, these demographic parameters do not influence significantly the quality of life of patients after anti-incontinence surgery. Parity does not show any significant influence on success rate of midurethral sling.
Highlights
Retropubic tension-free vaginal tape (TVT) or transobturator tape (TOT) are a standard of care for the surgical treatment of stress urinary incontinence in women [1]
Older patients seem to have a worse perception of improvement 5 years after surgery as compared to younger ones, as described by the Patient Global Impression of Improvement (PGI-I) score
Age and BMI do not affect significantly the quality of life of women surgically treated for stress urinary incontinence (SUI), as reflected by the results of Kings Health Questionnaire
Summary
Retropubic tension-free vaginal tape (TVT) or transobturator tape (TOT) are a standard of care for the surgical treatment of stress urinary incontinence in women [1]. These two procedures have been shown to have comparable outcomes with subjective cure rates of up to 85% [1,2,3]. The aim of this study was to perform a secondary analysis of these data, in order to assess if age, BMI and parity at the time of surgery may influence the short- and long-term outcomes of women primarily treated for SUI with midurethral tapes
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