Year-end Sale % OFF 
Abstract
THE DEVELOPMENT OF REPRODUCTIVE FUNCTION in female rats is materially altered by the injection of testosterone compounds during the first weeks of postnatal life (1–4). When these animals reach adulthood they show abnormalities in several features of reproductive structure and function. They do not display cyclic mating behavior; ovulation and corpus luteum formation do not occur; the uterus differentiates atypically and is not normally responsive to estrogen. When such animals are spayed and injected with estrogen and progesterone estrous behavior is not induced even with 10 times the quantity of hormone (3) which causes heat in control animals. It was concluded from these studies that testosterone propionate in doses from 3 to 36 mg. is effective in suppressing reproductive function when the injections are begun soon after birthOn the other hand, these androgens when given to sexually mature.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
