Influence of a nutritional supplement containing collagen peptides on the properties of the dermis

Abstract

The loss of dermal density and thickness, characterized by sagging and thinning skin, may be related to various conditions such as aging (both intrinsic and extrinsic) as well as abrupt changes in body mass – such as pregnancy or increased weight – and the resulting rupture of collagen fibers. Some nutrients can positively affect the dermal metabolism, thus improving its functional properties. Objective: To evaluate clinically and through ultrasound the effect of a nutritional supplement on the thickness of the dermis and on its functional properties. Methods: Twenty-eight female patients between the ages of 35 and 65 years, with facial sagging complaints, used the supplement for 90 days, having been evaluated subjectively and through ultrasound for clinical safety and efficacy. Results: The studied nutritional supplement provided a significant increase in dermal thickness after 30 days of use, in the areas evaluated. There was significant improvement in the firmness, elasticity, hydration and overall appearance of the skin. No adverse reaction related to the product was observed during the study period. Conclusions: The nutritional supplement was effective in improving the conditions of the dermis, increasing its thickness and clinical parameters of firmness, elasticity, and hydration, and has been proven safe and well-tolerated when used as instructed