Abstract

Heat and moisture exchanger (HME) filters are replacing heated humidifiers (HH) to promote humidification of inhaled air during mechanical ventilation. The argument is often that the HMEs are related to a lower incidence of VAP. On the other hand, a restriction to HMEs is that they are associated with an increased incidence of obstruction of the endotracheal tube. It is now known that the ventilator circuit and its accessories, including the humidification system, have very little impact on the incidence of VAP. The aspiration of contaminated secretions is the main determinant of this complication. The objective of this study was to compare the incidence of VAP in patients undergoing mechanical ventilation using HH versus HME filter. Secondarily, we analyzed the incidence of tracheal tube obstruction in both groups.

Highlights

  • Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition

  • The objective of this study was to verify the incidence of delirium through the CAM ICU instrument in ICU patients followed by physiotherapists

  • There was a low incidence of delirium in ICU patients followed by physiotherapists

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Summary

Introduction

Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition. The objective of this study was to evaluate the tendency of the plasma concentration and clearance of PCT as biomarkers for prognosis of patients with severe sepsis and septic shock, compared with another early prognosis marker, the number of SIRS criteria at sepsis diagnosis. The objective of this study was to evaluate the serum activity of MMP-2 and MMP-9, length of hospital stay, length of ICU stay and mortality in patients with septic shock. The objective of this study was to determine the influence of serum thiamine concentrations on lactate levels, GPx activity, length of hospital stay, length of ICU stay and ICU mortality in patients with septic shock. Hypothermia at ICU admission was associated with greater severity scores and increased hospital mortality in this sample of surgical patients studied.

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