Abstract
Background: IL-17 was recently described to be protective in mice immune response to Mycobacterium tuberculosis (Mtb). IL-22 mediates chronic T-cell inflammation. Little is known about the role of these cytokines in human tuberculosis (TB) infection. To investigate whether IL-17 and IL-22 contribute to the human anti-mycobacterial immune response we examined immune responses from blood and bronchoalveolar lavage (BAL) cells of healthy volunteers and patients with culture confirmed pulmonary TB.
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