Inflammatory response in patients requiring parenteral nutrition: comparison of a new fish-oil-containing emulsion (SMOF®) versus an olive/soybean oil-based formula

I Schade,A Schellhaass,J Boldt,Kd Röhm,A Mengistu,Sn Piper

doi:10.1186/cc6365

Abstract

Lipid emulsions are an essential part of parenteral nutrition (PN), such as energy supply and source of essential fatty acids. It has been shown that the composition of cell membranes is influenced by the fatty acid profile of dietary lipids, and may therefore be responsible for modulations in immune response. The aim of this study was to assess the effects of a new lipid emulsion based on soybean oil, medium-chain triglycerides, olive oil and fish oil (SMOF®) compared with a lipid emulsion based on olive and soybean oil (ClinOleic®) on the inflammatory response in postoperative ICU patients.

Highlights

The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality
The goal from this study is to evaluate weaning predictor indexes in patients during weaning from mechanical ventilation (MV)
This study aims to evaluate the effects of the threshold in such situations

Summary

Introduction

The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality. Methods A total of 48 community patients (36 men, 11 women, age 50.17 ± 17.974 years, APACHE II score 13.51 ± 6.153) who were expected to stay in the ICU for >5 days were included in this study. Specific examples of feedback are as follows: ‘good update of management plan reinforces need for taking into account concurrent medication when resuscitating patients’, ‘nice simple messages with good starting points for trying to deal with these complicated patients’, ‘useful data on risk of recurrence as this is a question often asked by patients’ This feedback was encouraging as it showed how the primary care professionals planned to change their practice to improve patient outcomes as a result of the learning. The course was considered excellent by 63% of the participants and good by 36%

Methods

Results

Conclusion