Abstract
Inflammatory myofibroblastic tumors are uncommon neoplasms; presentation of these tumors in the lower extremities is extremely rare. We present a case of a 47-year-old male with fever, fatigue, and a slow-growing thigh mass. The inflammatory markers were elevated and the MR images showed a well-defined intermuscular lesion with mild heterogeneous enhancement. The lesion was excised and histologic examination was consistent with an inflammatory myofibroblastic tumor. No adjuvant therapy was needed and the patient remained asymptomatic with no evidence of tumor recurrence during the 2 years of follow-up.
Highlights
Inflammatory myofibroblastic tumours (IMT) have emerged from a broad category of inflammatory pseudotumours, with distinctive clinical, pathological, and molecular features [1]
These tumors were referred as plasma cell granulomas, xanthomatous pseudotumors, pseudosarcomatous myofibroblastic proliferations, myofibroblastomas, inflammatory myofibrohistiocytic proliferations, and inflammatory pseudotumors [6,7,8]
IMTs have emerged from a broad category of inflammatory pseudotumours, with distinctive clinical, pathological and molecular features
Summary
Inflammatory myofibroblastic tumours (IMT) have emerged from a broad category of inflammatory pseudotumours, with distinctive clinical, pathological, and molecular features [1]. According to the World Health Organization IMTs are classified as tumors of intermediate biological potential due to a tendency for local recurrence; they rarely metastasize [2,3,4,5]. In the past, these tumors were referred as plasma cell granulomas, xanthomatous pseudotumors, pseudosarcomatous myofibroblastic proliferations, myofibroblastomas, inflammatory myofibrohistiocytic proliferations, and inflammatory pseudotumors [6,7,8]. In this paper we aimed to present the unique clinical and radiographic features of this rare tumor, the differential diagnosis and treatment options through a review of the current literature
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