Inflammatory myofibroblastic tumor of the lacrimal gland: case report of an exceptional location

Adil Boudhas,Mohamed Oukabli,Fouad El Asri,Hafsa Chahdi,Mohamed Reda El Ochi,Abderrahmane Al Bouzidi,Issam Rharrassi,Mohamed Allaoui,Mohamed Tbouda

doi:10.1186/s12907-017-0050-3

Adil Boudhas, Mohamed Oukabli + Show 7 more

Open Access

https://doi.org/10.1186/s12907-017-0050-3

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Journal: BMC clinical pathology	Publication Date: Aug 17, 2017
Citations: 2	License type: open-access

Affiliation: Mohammed V University

Abstract

BackgroundInflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-abdominal soft tissues.Case presentationWe report here an exceptional case of inflammatory myofibroblastic tumor arising in the lacrimal gland and presenting as an orbital mass in a 24-year-old male.ConclusionThis report aims to discuss the importance of histopathological and immunohistochemical findings in arriving at the diagnosis, which helps dictate the management, treatment and prognosis of the patient.

Highlights

Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-abdominal soft tissues
Half of Inflammatory myofibroblastic tumor (IMT) have a rearrangement of the anaplastic lymphoma kinase (ALK)
We present here an exceptional case of orbital IMT occuring in the lacrimal gland

Summary

Introduction

Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-abdominal soft tissues. Case presentation: We report here an exceptional case of inflammatory myofibroblastic tumor arising in the lacrimal gland and presenting as an orbital mass in a 24-year-old male. Inflammatory myofibroblastic tumor (IMT) is a very rare mesenchymal tumour that can arise in various anatomic locations [1, 2]. Half of IMTs have a rearrangement of the anaplastic lymphoma kinase (ALK). This entity is quite curable if completely and appropriately excised [1,2,3]. We present here an exceptional case of orbital IMT occuring in the lacrimal gland. Case presentation A 24-year-old male, was referred to our medical institution with a 4 months history of progressive and indolent mass in the super-external area of the left eye with no notion of trauma or insect bite

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Conclusion