Inflammatory markers and Nutrients intake in Korean patients with non alcholic fatty liver

Abstract

The purpose of this study was to examine the correlations between fatty liver disease, obesity, blood inflammatory markers, biochemical indicators, and diet. The subjects included 40 males and 40 females who visited the Health Promotion Center at the S University Hospital. Among the participants, 22 males (55.0%) and 10 females (25.0%) were diagnosed with non‐alcoholic fatty liver disease. The study reported that subjects in the fatty liver group (FLG) had a significantly higher mean body mass index, body fat content, and WHR than those in the non‐fatty liver group (NFLG). In addition, subjects in the FLG had higher levels of serum ALT, γ‐glutamyl transpeptidase, cholesterol, and triglycerides than those in the NFLG. The mean level of adiponectin, an inflammatory marker, was significantly lower in male and female subjects in the FLG than those in the NFLG, and the C‐reactive protein and tumor necrosis factor‐α levels were significantly higher in female subjects in the FLG than those in the NFLG. The subjects in the FLG had significantly higher levels of metabolic syndrome indicator, and approximately 60% of the female subjects in the FLG also had metabolic syndrome. Male subjects in the FLG had significantly higher intake of sodium, vitamin A, and saturated fatty acids but lower intake of iron than those in the NFLG. Female subjects in the FLG had significantly higher intake of calories, carbohydrates, iron, sodium, cholesterol, and saturated fatty acid but lower intake of vitamin B6 than those in the NFLG.The adiponectin level was significantly lower in all subjects in the FLG than those in the NFLG.