Abstract

Despite extensive effort on studying inflammatory processes in the CNS of Parkinson's disease (PD) patients, implications of the peripheral immune system are still poorly understood. In particular, the role of peripheral blood monocytes remains elusive. Here, we set out to obtain a comprehensive picture of circulating myeloid cells in PD patients. We applied a human primary monocyte culture system and flow cytometry based techniques to functionally characterize monocytes from PD patients during disease.

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