Abstract
To compare octyl-2-cyanoacrylate (2-OCA) tissue adhesive with subcuticular suture for the closure of incisions in the maxillofacial region to determine 1) whether it is faster than traditional subcuticular suturing, 2) whether the number and length of incisions affect closure time, 3) wound morbidity, 4) patient satisfaction outcome, and 5) cosmetic outcome.In a prospective randomized clinical trial, 29 patients were allocated to 1 of 2 groups for the closure of skin incisions using 2-OCA or conventional subcuticular skin sutures. Postoperative follow-up evaluated wound healing at 5 to 10 days and at 3 months. Assessment of cosmetic outcome was performed by a plastic surgeon using a modified Hollander Wound Evaluation Scale and a validated visual analog scale. Comparisons between groups were performed using the Student t test and χ2 test.Twenty incisions in 14 patients were closed with 2-OCA and 20 incisions in 15 patients were closed with subcuticular sutures. Mean time of closure was significantly (P < .005) faster with 2-OCA at 69.50 ± 33.39 seconds compared with 379.00 ± 75.39 seconds in the suture group. There was no significant difference in wound complications between the 2 groups; also, there was no significant difference in patient satisfaction and cosmetic outcome of scars at the 3-month follow-up between the 2 groups.2-OCA tissue adhesive is an excellent alternative to sutures for effective, reliable, and faster skin closure of maxillofacial incisions.
Highlights
Studies of inflammatory bowel disease (IBD) over many decades have spanned a wide range of topics from clinical epidemiology and diagnosis, through dietary and pharmacologic therapy and immunologic and biologic etiology, to pathophysiologic links to malignancy
In this special issue devoted to IBD, the Guest Editors and one of the authors have selected a series of seven papers from seven countries that reflect this entire spectrum
Correa et al from the University of Puerto Rico call our attention to the increasing prevalence of both ulcerative colitis (UC) and Crohn’s disease (CD) among Hispanics
Summary
Sachar,1 Derek Jewell,2 Christoph Gasche,3 and Jonathan Braun4 Studies of inflammatory bowel disease (IBD) over many decades have spanned a wide range of topics from clinical epidemiology and diagnosis, through dietary and pharmacologic therapy and immunologic and biologic etiology, to pathophysiologic links to malignancy. In this special issue devoted to IBD, the Guest Editors and one of the authors have selected a series of seven papers from seven countries that reflect this entire spectrum.
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