Inflammation of the Dental Pulp

Sang Hyuk Park,Hiromichi Yumoto,Robert M Love,Jean-Christophe Farges,Ling Ye

doi:10.1155/2015/980196

Abstract

Inflammation of the Dental Pulp

Highlights

This special issue is published with the intent of disseminating current knowledge and findings on inflammation in the dental pulp
It is unique in a way that its soft tissues are enclosed within mineralized hard tissues, and its pulp is supplied by a rich neurovascular network that regulates various inflammatory mediators [1, 2]
A thorough understanding of the pulpal inflammatory process is essential in the development of proper dental procedures and immunotherapeutic agents. This issue highlights the molecular mechanisms of inflammatory cascades, immunomodulatory effects of various substances, techniques used to study inflammation and regeneration of the dental pulp, and why an understanding of inflammatory process is important in the field of endodontics

Summary

Introduction

This special issue is published with the intent of disseminating current knowledge and findings on inflammation in the dental pulp. Factors that induce inflammation in the dental pulp and the root apex are as follows [1, 2, 5, 6]: the ingression of microorganisms through dental caries, crack or dentinal tubules of the teeth; chemical irritation from etching and/or bonding materials for adhesion of dental materials; mechanical irritation during preparation in restorative procedures; trauma from occlusion (TFO) or orthodontic movement of the teeth. Such factors may initiate the inflammatory cascades, which, in turn, further progress to pain and root resorption via neurogenic inflammation and hard tissue remodeling [7,8,9].

Results

Conclusion