Infiltrative Lobular Breast Carcinoma Presenting Initially as an Orbital Metastatic Lesion

Abstract

The incidence of orbital metastases is estimated to be 1-2 per year in large centers. The commonest orbital metastasis is from breast cancer, which tends to occur late followed by lung cancer which tends to occur relatively early in addition to a proportion of metastatic lesions from unknown primary sites. The metastatic breast lesions to the orbit can be discovered as late as 20-25 years following the identification of the primary tumor. However, the orbital metastatic lesion can be the initial manifestation in a small number of patients. We are presenting a 48-year-old female patient where the diagnosis of her lobular breast carcinoma was made after her initial presentation to the ophthalmic service because of diplopia. Her clinical course, histopathological findings of her orbital lesion as well as the radiological findings are described with extensive review of the most recent literature.