Inferior Frontal Lobe Position after Endoscopic Anterior Skull Base Resection and Repair with Acellular Allograft

Abstract

Background: Reconstruction methods for large anterior skull base defects vary without consensus on the optimal reconstruction to achieve a water-tight seal and anatomic frontal lobe position. Many have described the use of multilayer closure utilizing a septal flap with excellent results. Unfortunately, a septal flap may not always be available in extensive resections. High success has been reported with single layer reconstruction using acellular allograft. However, it is unclear if there is sufficient support with a single layer reconstruction to achieve anatomic frontal lobe positioning.