Abstract

Introduction: The incidence of early -onset group B streptococcus (GBS) disease has decreased substantially due to universal antenatal culture screening of pregnant women for GBS colonization at 35 -37 weeks of gestation and the widespread use of intrapartum antibiotic prophylaxis. However, the incidence of late-onset GBS disease has remained constant in the past decade and it is unaffected by maternal intrapartum chemoprophylaxis. Late-onset GBS infection affects infants who had an unremarkable maternal obstetric and early neonatal history. Other sources rather than vertical route, like horizontal transmission from hospital or community, albeit less frequently proved, can justifies late onset GBS disease.Case report: This case report illustrates a late-onset GBS disease, presenting as neonatal septic arthritis on a caucasian term infant, with unknown route of transmission and highlights the morbidity associated.Discussion: Additional research pertaining to the transmis- sion of late-onset GBS infections is required to develop effective preventive methods.

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