Abstract

It is of interest to recall some of the advances made in the field of infectious diseases in the brief ten year period since these reviews have been prepared. Needless to say, the discovery and practical application of the sulfonamide compounds in 1935 and of penicillin in 1940 by European investigators were of epochal importance. The use of these substances has already caused a great reduction of the mortality rate and severity of diseases caused by pneumococci, hemolytic streptococci, staphylococci, meningococci and gonococci. So great is the value of these innovations that the use of other specific therapeutic agents for infections caused by some of these bacteria is nearly obsolete. Penicillin has the three properties of the ideal antiseptic which have long been sought without serious expectation of ever finding them combined in one substance, namely, enormous antiseptic power, almost complete indifference to the medium in which it acts and

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