Abstract

Syphilis is a sexually transmitted infection caused by the spirochete Treponema pallidum. Left untreated, the disease progresses through four stages. Posterior segment involvement may occur at any stage of the disease and may include intermediate and posterior uveitis, chorioretinitis, retinitis, retinal vasculitis, and optic neuropathy. Diagnosis of syphilis is based on high level of clinical suspicion and supported by a combination of treponemal-specific and nontreponemal serological tests. All patients with newly diagnosed syphilis should be tested for coinfection with human immunodeficiency virus, as the risk factors are similar for both diseases. Patients with ocular syphilis should be treated as neurosyphilis with aqueous penicillin G or procaine penicillin G plus probenecid.KeywordsRetinal Pigment EpitheliumRetinal Vein OcclusionBranch Retinal Vein OcclusionRetinal VasculitisCongenital SyphilisThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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