Abstract
In this special issue of Journal of Pediatric Infectious Disease, we have compiled eight cutting-edge review articles addressing the prevention, diagnosis, and management of infections in children with a spectrum of kidney disease ranging from neonatal sepsis-associated acute kidney injury (AKI) to the infectious complications of chronic kidney disease including end-stage renal disease (ESRD) on different modalities of renal replacement therapy. The burden of infections in this vulnerable population has been profound despite major improvements in the care of children with acute and chronic kidney disease (CKD) in the past few decades. The survival rate of children with ERSD remains approximately 30 times lower than that of healthy peers[1] [2] with infection being one of the leading causes of death. In addition to the morbidity and mortality associated with infections, infection-related hospitalizations contribute substantially to reduced quality of life, increased school absences, increased health care costs, etc.
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