Abstract

We conducted a serosurvey of 155 healthcare workers and 124 household and community members who had close contact with 18 patients who had laboratory-confirmed Nipah virus infections in Kerala, India. We detected 3 subclinical infections; 2 persons had IgM and IgG and 1 only IgM against Nipah virus.

Highlights

  • We conducted a serosurvey of 155 healthcare workers and 124 household and community members who had close contact with 18 patients who had laboratory-confirmed Nipah virus infections in Kerala, India

  • Nipah virus (NiV) is known to cause subclinical infections, the extent of these infections among close contacts varies during outbreaks

  • No subclinical infections have been reported from outbreaks in Bangladesh [11], but 1%–15% of infections were subclinical during outbreaks in Malaysia [12,13,14,15]

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Summary

Introduction

We conducted a serosurvey of 155 healthcare workers and 124 household and community members who had close contact with 18 patients who had laboratory-confirmed Nipah virus infections in Kerala, India. The initial case-patient was hospitalized on May 3, 2018, but his blood sample could not be collected for laboratory confirmation of NiV. Sixteen patients with laboratory-confirmed NiV infection died (casefatality rate 89%). As part of contact tracing, district health authorities identified ≈2,600 contacts of laboratory-confirmed NiV patients.

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