Infection with possible precursor of avian influenza A(H7N9) virus in a child, China, 2013.

Lili Ren,Jianwei Wang,Baihui Zhao,Fan Wu,Xi Zhang,Qi Jin,Xuelian Yu

doi:10.3201/eid2008.140325

Abstract

During the early stage of the avian influenza A(H7N9) epidemic in China in March 2013, a strain of the virus was identified in a 4-year-old boy with mild influenza symptoms. Phylogenetic analysis indicated that this strain, which has similarity to avian subtype H9N2 viruses, may represent a precursor of more-evolved H7N9 subtypes co-circulating among humans.

Highlights

Updated on 15 April 2013 The WHO Collaborating Center for Reference and Research on Influenza at the Chinese National Influenza Center, Beijing, China, has made available attached realtime RT-PCR protocol for the detection of avian influenza A(H7N9) virus
It is strongly recommended that all unsubtypeable influenza A specimens should be immediately sent to one of the six WHO Collaborating Centres for Influenza in the Global Influenza Surveillance and Response System (GISRS)[1] for testing and analysis
To detect avian influenza A(H7N9) virus using real-time RT-PCR with specific primers and probes targeting the matrix, H7 and N9 genes

Summary

Introduction

Updated on 15 April 2013 The WHO Collaborating Center for Reference and Research on Influenza at the Chinese National Influenza Center, Beijing, China, has made available attached realtime RT-PCR protocol for the detection of avian influenza A(H7N9) virus. Real-time RT PCR (rRT-PCR)Protocol for the Detection of A(H7N9) Avian Influenza Virus (April 15, 2013)

Results

Conclusion