Abstract
Infection of Long-Term Tunneled Catheter for Hemodialysis: Impact of Prevention Protocols on the Rate of Infections and on Bacterial Ecology
Highlights
The prevalence of haemodialysis is expected to annually increase by 4% due to increased life expectancy and progression of pathologies leading to renal failure [1]
Gentamicin lock was associated with a reduction in catheterrelated bacteraemia (CRB) incidence from 1.96 to 0.29 per 1000 catheter-days (p
Heparin alone was associated with a decrease of resistance but a higher CRB incidence of 0.63, despite reinforcement of hygienic rules
Summary
The prevalence of haemodialysis is expected to annually increase by 4% due to increased life expectancy and progression of pathologies leading to renal failure [1]. Infection either localized or systemic, is the major source of morbidity and mortality among haemodialysis patients. The main source of these infections is bacteremia associated to vascular access, implied in 48 to 73% of them [4] and responsible for 26% of catheter withdrawals [5]. The relative risk of bacteraemia is 7.64 fold higher in patients requiring catheter compared to those having a native arteriovenous fistula, as shown in a prospective study involving 988 end-stage renal disease patients [10]. Infection is the major source of morbidity and mortality among hemodialysis patients, mainly due to bacteremia associated to vascular access.
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