Abstract
Epizootic haemorrhagic disease of deer virus, an orbivirus related to bluetongue virus, was inoculated intravenously into red, fallow, roe and muntjac deer, and into sheep, goats, pigs and cattle. Low level viraemias were recorded in each species apart from goats and pigs but clinical disease was not observed. Virus was not isolated from swabs taken of the nasal, urogenital or rectal mucosae. Control animals in direct contact with inoculated animals did not develop a detectable viraemia or serum antibody. In viraemic animals the virus was associated with the cell fraction of the blood. Beyond 7 days after inoculation the chance of virus isolation was enhanced if the cells were washed and lysed prior to inoculation of the cell cultures. It is suggested that cattle may play a role in the epizootiology of epizootic haemorrhagic disease of deer in North America.
Published Version
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