Abstract
The article in this issue by Richter et al outlines a prospective observational study of patients undergoing suprapubic prostatectomy.1 Patients had urine cultures performed 48 to 72 hours before scheduled surgery, but the presence of infected urine was not considered to be a contraindication to surgery. Antimicrobial therapy was initiated at the time of prostatectomy with either oral trimethoprim sulfa or another specific antibmicrobial agent chosen according to the antimicrobial susceptibilities of the urinary pathogen. The authors documented a high rate of postoperative incisional wound infection (23.5%) among patients with infected urine, as compared to an 8.7% rate among individuals with clean urine at the time of surgery. The difference was both statistically (p = .028) and clinically significant.
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